|
KMID : 1004820140150030117
|
|
Journal of Biomedical Research
2014 Volume.15 No. 3 p.117 ~ p.122
|
|
|
Antibacterial effects of carvacrol against Staphylococcus aureus and Escherichia coli O157:H7
|
|
Cho You-Young
Lee Hu-Jang
|
|
|
Abstract
|
|
|
|
The objective of this study was to investigate the antimicrobial effects of carvacrol (CV) against Staphylococcus aureus (S. aureus) and Escherichia coli O157:H7 (E. coli O157:H7) strains in milk. The minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) of CV against S. aureus and E. coli O157:H7 were determined. In addition, bactericidal kinetics and antimicrobial activity of CV against the aforementioned pathogens in milk over a period of 2 weeks were investigated. CV exhibited antibacterial activity against both foodborne pathogens tested. The MIC and MBC of CV against S. aureus were 15.0 and 20 mg/mL, respectively, whereas those against E. coli O157:H7 were 16.0 and 32 mg/mL, respectively. In time-kill assays, CV at MBC reduced the number of S. aureus and E. coli O157:H7 in milk to undetectable levels within 24 hr. The antibacterial effects of CV persisted for 14 days without any loss of activity. Results of this study suggest that CV has a potential antibacterial activity against foodborne pathogens such as S. aureus and E. coli O157:H7 in milk.
|
|
|
KEYWORD
|
|
|
foodborne disease, carvacrol, antibacterial activity, Staphylococcus aureus, Escherichia coli O157:H7
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|